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Instant Pot Mississippi Pot Roast

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Instant Pot Mississippi Pot Roast is one of the most amazing pot roasts you can make in the instant pot. Buttery, juicy, tender and full of pepperoncinis, ranch and au jus flavors.

Instant Pot Mississippi Pot RoastInstant Pot Mississippi Pot Roast is such a fantastic meal, that you just can’t miss it out. This is probably my favorite way to cook pot roast. The beef is so incredibly tender, that it melts in your mouth. Cooked with butter, ranch dressing dry mix and au jus mix, the beef is infused with so much flavor. Instant Pot Mississippi Pot Roast is famous for the pepperocinis that are being cooked with the beef and add just the right amount of heat. Adding pepperocinis juice, adds another layer of flavor, you will end up with such a creamy and perfect gravy that is incredibly tasty over that juicy beef.

Looking for more easy Instant Pot Beef Meals? Check these out:

  1. Instant Pot Beef Bourguignon
  2. Instant Pot Mongolian Beef
  3. Instant Pot Philly Cheesesteak Pasta
  4. Cheesy Instant Pot Taco Pasta
  5. Instant Pot Jalapeno Popper Pasta
  6. Instant Pot Pizza Pasta
  7. Instant Pot Best Chili
Instant Pot Mississippi Pot Roast

Tips & Tricks on how to make the perfect Instant Pot Mississippi Pot Roast Recipe:

  • I always say this, but a good meat centered meal starts with quality meat, preferably use organic beef for this meal. Use grass-fed chuck roast possible, grass-fed meet tends to be extra tender, which is perfect in this recipe.
  • Look for fresh meat, that has a bright color, and lots of marbling, the marbling is essential to get great flavor and tenderness.
  • Cut the chunk into two pieces if needed, as you will have to brown it in batches.
  • Browning the beef is essential, it will lock the flavor and the beef juices and also elevate the meat flavor.
  • I used lots of garlic in this recipe, we love garlic in our family and I think it works really well with the flavors. Feel free to use less if you are not a huge garlic fan. Don’t worry about it being too garlicky, leaving the garlic cloves whole, makes the release just the right amount of flavor and will produce a fantastic gravy.
  • You can add more red pepper flakes for the dish to be spicier.
  • Use low sodium beef broth, you don’t want to end up with a salty pot roast.
  • The bay leaves are optional, but they will add a subtle, nice flavor to the gravy and beef.
  • Au Jus dry mix can be replaced with brown gravy mix.
  • Store the Instant Pot Mississippi Pot Roast in a large airtight container in the fridge, make sure that the gravy liquid covers at least partially the beef, so it won’t dry out.
  • Instant Pot – I have the 6 quarts one. It makes weeknight meals so much easier.

Looking for Instant Pot Side Dishes? These are my favorites:

  1. Fluffy and Creamy Instant Pot Mashed Potatoes
  2. The Best Instant Pot Sweet Potatoes
  3. Low Carb Instant Pot Mashed Cauliflower
Instant Pot Mississippi Pot Roast

Why browning the chuck roast is important?

Browning will lock in all the fantastic flavors, and will give the beef that delicious, caramelized top on the outside, that reveals a juicy and tender inside. I highly recommend that you cut the chuck roast in half, so it fits in the Instant Pot, and make sure you brown it well for a few minutes on each side without moving the beef. While you can dump and cook all the ingredients, taking the extra few minutes to brown the beef, will make a huge difference in taste and texture.

What is a 15 Minutes Natural Pressure Release?

A Natural Pressure Release means that the pressure is released gradually. For a Natural Pressure Release, you click on Keep Warm, and wait 10 minutes, after which you open the valve and let any leftover pressure to release. Another option is to Turn Off/Unplug the pressure cooker, wait 15 minutes and after that open the valve. A natural release is usually used when cooking soups, meat in a large amount of sauce, pasta or steel cut oats. This method prevents for any foam from the dish to shoot out through the valve, which can happen during a Quick Pressure Release.


Here is a step-by-step video of how to make the Instant Pot Mississippi Pot Roast Recipe:

Instant Pot Mississippi Pot Roast
4.89 from 9 votes

Instant Pot Mississippi Pot Roast


  • 5 lbs chuck roast cut 2 chunks that would fin in the pot
  • 3 tablespoons vegetable or canola oil
  • 1 small onion diced
  • 1 tablespoon minced garlic
  • 1/2 cup water
  • 1/2 cup Pepperoncini juice from the jar
  • 3/4 cup Beef Broth low sodium
  • 1 tablespoon Worcestershire sauce
  • 1/2 teaspoon salt
  • 1/2 teaspoon ground black pepper
  • 1/4 teaspoon red pepper flakes
  • 1 packet of dry Ranch Dressing Mix
  • 1 packet of Au Jus Mix
  • 12 Pepperoncinis whole
  • 1 stick unsalted butter sliced
  • 8 garlic cloves whole
  • 5 bay leaves
Cornstarch Slurry:
  • 2-3 tablespoons cornstarch
  • 3 tablespoons water


  1. Set Instant Pot to Saute - Normal mode. When it reads "Hot" add the oil and wait for the oil to heat up.
  2. Brown the meat in batches. If needed cut the chuck roast in two, so it fits in the pot. Cook each piece on EACH side for full 5 minutes without turning.
  3. If needed, add a bit more oil to the pot when searing the rest of the pieces.
  4. Remove the seared pieces on a plate and cover with foil to keep them warm.
  5. Once all the beef has been browned and set aside its time to deglaze the pot.
  6. Add the 1/2 cup of water to the pot and using a wooden spoon scrape the bits and pieces that stuck to the bottom and sides of the pot until its cleared.
  7. Add onion and minced garlic and cook for 1 minute, stirring occasionally.
  8. Add the beef broth, Pepperoncini juice and Worcestershire sauce.
  9. Add the salt, pepper, red pepper flakes, Ranch dressing dry mix and Au Jus mix. Stir to combine.
  10. Turn off the sauté mode.
  11. Add the beef in layers, and add sliced butter and garlic cloves between each layer.
  12. Add the Pepperoncinis to the pot as well as bay leaves.
  13. Close the lid and seal the valve. Cook for 60 minutes on High Pressure. Once the Instant Pot beeps, do a 15 Minute Natural Pressure Release. Release manually the remaining pressure.
  14. Open the lid and turn the Instant Pot to Sauté mode.
  15. If you want the gravy to be thicker, mix cornstarch and water in a small bowl until fully combined.
  16. Add the mixture to the pot and gently stir. Let it simmer for 2-3 minutes. If you want to thicken it even more, add another round of cornstarch slurry. The sauce will thicken more as it cools off as well.
  17. Discard the bay leaves and serve the roast with mashed or baked potatoes. Garnish with extra Pepperoncinis and chopped parsley.

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Instant Pot Mississippi Pot Roast
Instant Pot Mississippi Pot Roast is one of the most amazing pot roasts you can make in the instant pot. Buttery, juicy, tender and full of pepperoncinis, ranch and au jus flavors.
Instant Pot Mississippi Pot Roast is one of the most amazing pot roasts you can make in the instant pot. Buttery, juicy, tender and full of pepperoncinis, ranch and au jus flavors.

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31 comments on “Instant Pot Mississippi Pot Roast”

  1. OK now this sounds delicious – I have to admit I’ve not tried cooking with an instant pot before but it sounds like you can do so much with one, I need to try it out myself!

  2. This is such a fantastic dinner! Anything I can make in the Instant Pot is a winner in my book!

  3. Wow, I really need to get an Instant Pot and finally make this Mississippi pot roast, looks so good.

  4. I don’t make pot roasts nearly enough so thank you for the inspiration! Yours looks so juicy and tender!

  5. This looks like a delicious recipe to try to make. I love all of these Instant Pot recipes everyone is sharing, they are making my tummy growl!

  6. This looks so yummy and comforting! I love easy instant pot recipes!

  7. This recipe looks so delicious. The meat looks so supple and flavorful, and not hard to prepare.

  8. Another great recipe find for the instant pot. Garlic, and lots of it, really caught my eye!

  9. This looks so good, yum! I love how easy it is to make. Now I badly need an instant pot.

  10. My sister makes a roast similar to this in her Instant Pot. I’d like to try your version as well.

  11. I swear by a good old pot roast meal. This is a super awesome recipe. Thanks so much for sharing all your recipes!

  12. What a unique pot roast recipe. This sounds wonderful and definitely something I’ll try. I don’t cook in our Instant Pot nearly as much as I should!

  13. I have to confess, I have never mad a pot roast!!! This recipe looks absolutely delicious!

  14. Wow, this is killer. I would love to try this recipe out sometime!

  15. This needs to happen at my house very soon!!

  16. Can I use a frozen pot roast? If so do I need to change anything?

  17. That looks delicious! I really need to get me an Instant Pot ASAP so I can cook all these Instant Pot recipes.

  18. I love pot roast but my husband doesnt like it. Its a shame. 🙁 I love mine in a broth, onions, baby carrots, and taters. Yum. I will have to make it soon. Maybe I can twist my husband to try it.

  19. This recipe looks so good and tasty and this is kind of a perfect dish for lunch or even for a dinner. I will definitely make this recipe for my family.

  20. I love how spicy this pot roast is! It looks so delicious!

  21. This is the best roast recipe!

  22. I found the same recipe but using a pork roast. It was cooked in a crockpot and used dry onion soup mix with the ranch mix. How long do you think it will need to cook in the instant pot? It showed 6 hours in the crockpot.

    • For a cut of pork shoulder or butt recipe that is 2 lbs I would do 10 mins HP & 10 NPR if you pre-slice the pork, or if you add the whole piece, about 40min on HP and 10 NPR, depending on the thickness of the cut you can increase the cooking time to 60 mins on HP and 10NPR.

  23. I’m thawing a 3 pound chuck roast and plan to use your recipe. Will the cook time be any different since my roast is smaller? Thanks, in advance. 

  24. This looks great. For Instant Pots that let you choose the sauté temperature like the Ultra, do you recommend high or medium to brown the roast? Thanks!

  25. Excellent! I followed the recipe exactly and it was perfection. Probably the best roast I’ve ever had or made! Thank you!

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