Instant Pot Mississippi Pot Roast

When asked what my favorite comfort meal is, I instantly say Instant Pot Mississippi Pot Roast – buttery, juicy, tender, and full of pepperoncini, ranch, and au jus flavors. The meat is tender, the gravy is rich, and it takes only about one hour to pressure cook.

A forkful of incredibly tender instant pot Mississippi pot roast.

I love making easy and delicious Instant Pot recipes, such as my famous Orange Chicken, Instant Pot Ribs, and Mongolian Beef. This smart kitchen gadget completely redefined how I cook and how I approach meal-planning for busy weeknights. I can rely on it to have a cozy home-cooked meal prepared with minimum effort and stress-free. Now I am excited to get in the kitchen, and I am not even worried if I forgot to thaw the meat, because I can make a pot roast even with frozen beef.

A good pot roast is the epitome of comfort food, and this one is irresistible. I brown the beef to lock in all the juices and cook it in a zesty and tangy mix of pepperocini, ranch, and butter, yes, lots of butter. The meat gets incredibly tender and succulent, while the gravy is so creamy and rich. Honestly, it tastes incredibly fancy, as if it’s been slowly cooked for hours and hours. But in reality, this is one of the most effortless meals you can make!

Succulent instant pot Mississippi pot roast with pepperoncini over mashed potatoes.

Why you will love this recipe 

  • It’s pot roast in a hurry: I love pot roast, but it always takes so long. My IP recipe takes just an hour to prepare and is ready to serve with delicious gravy for dipping. So easy to make for a weeknight comfort meal!
  • Easy to make: With the Instant Pot, I can just put it all in, turn it on, and let it cook. No stirring or checking. I love a home-cooked meal that doesn’t require too much effort, and the result is like something that has been slowly cooked for hours.
  • One-pot meal: I love one-pan meals because they require less cleanup. Stress-free, low-effort meals are my favorites, and this one is fully prepared in the Instant Pot, making clean-up a breeze.
  • Tender and delicious: The meat is just falling off the fork and melting in your mouth, and the flavor is incredible. 

What you will need

Overhead shot of instant pot mississippi pot roast ingredients arranged on a table.
  • Meat: Chuck roast is the best cut for this recipe. I cut mine into chunks so it will fit. 
  • Wet ingredients: I use low-sodium beef broth to avoid a too-salty taste. A tablespoon of Worcestershire sauce gives the gravy a dose of umami flavor with sweet, salty, savory, and tangy tastes. I also add some pepperoncini juice from the jar, as it tenderizes the meat and adds a slightly spicy flavor. To give the roast an extra buttery taste, I add a whole stick of butter to the pot as well. 
  • Dry ingredients: The diced onion and minced garlic give it extra flavor and texture, much fresher than powder. I also add whole garlic cloves to the pot for a more robust garlicky taste. The pepperoncini are the trademark flavor for the Mississippi pot roast, as they are known for the southern state. The flavor of the peppers and how they tenderize the meat is what makes this recipe so popular. 
  • Seasonings: To make the gravy taste incredible, I add a packet of au jus mixture for a rich beefy flavor and ranch dressing seasoning to add extra tanginess with more garlic and onion, as well as buttermilk, chives, dill, and parsley. 
  • Herbs and spices: I add bay leaves for complex layers of flavor, red pepper flakes to give it a little bit more heat, and salt and pepper to taste.  

How to make 

Brown the roast: First, I heat the oil on sauté mode to brown the meat on each side for five minutes after seasoning it with salt and pepper. When each piece is browned on both sides, I put them on a plate covered in foil while I finish the rest of the meat. 

Searing beef roast in the Instant pot.

Deglaze the pot: Then, I deglaze the pot with ½ cup of water or beef broth, using a wooden spoon to scrape the bits from the bottom and sides. The minced garlic and chopped onion go into the pan now, to cook for one minute, stirring occasionally, before stirring in the broth, pepperoncini juice, Worcestershire sauce, au jus mix, ranch dressing mix, red pepper flakes, salt, and pepper. 

Deglazing the instant pot by scraping the bottom with a wooden spoon.

Cook the roast: Next, I turn off the sauté mode and add the meat, chunks of butter, and garlic cloves, mixing them evenly. Then, I top that with pepperoncini and lay the bay leaves on top of it. After, I close the lid and cook it for 70 minutes on high. 

Instant pot Mississippi pot roast with pepperoncini.

Thicken the gravy: After it is done, I perform a 15-minute natural release before manually releasing the remaining pressure. Then, I open the pot and turn it to sauté again. I add cornstarch slurry if it needs to be thickened and let it simmer for two minutes, stirring occasionally. 

Instant pot Mississippi pot roast/

Serve with sides: Finally, I turn off the pot, discard the bay leaves, and serve the roast with gravy and my favorite side dishes. 

Expert tips

Why browning the chuck roast is important

Browning will lock in all the fantastic flavors and will give the beef that delicious, caramelized top on the outside, which reveals a juicy and tender inside. Also, I highly recommend cutting the chuck roast in half to fit in the Instant Pot. Be sure to brown it well for a few minutes on each side without moving the beef. While you can dump and cook all the ingredients, taking the extra few minutes to brown the meat will make a huge difference in taste and texture.

Using a natural pressure release

One of the most important tips that many people get wrong is to use a natural pressure release after the cooking process. Even if everything is done perfectly and it is cooked exactly as the recipe states, skipping this one step can mess everything up. Allowing the roast to cool slowly in the residual heat makes the meat so much more tender and full of flavor. A quick release instead of a natural release can push the moisture out of the meat and cause it to be dry.

More tips to consider:

  • Find a chuck roast with plenty of marbling for the best results.
  • Season the meat with salt and pepper before searing it.
  • Use unsalted butter. The seasonings have plenty of salt. 
  • Be sure to deglaze the pot to avoid the burn notice. 
  • Chop the butter into small pieces so it melts evenly within the chunks of meat.
Overhead shot of tender, instant pot Mississippi pot roast over mashed potatoes.

Recipe variations and add-ins:

  • Add veggies: Sometimes, I add vegetables to make this a whole meal. But they have to be whole potatoes and carrots that can stand up to an hour of cooking under pressure. 
  • Hot and spicy: To add some spiciness to this roast, add a few jalapeno peppers to the pot. Remember to remove the seeds and membranes to avoid making the dish too spicy. 
  • Make it sweet: For those who like a little more sweetness in their dinner, add some brown sugar to the mix. 
  • Cajun roast: I like to replace the ranch seasoning with my Cajun seasoning for a unique spiciness that goes great with my dirty rice.      
  • Pork roast: Another way to enjoy this dish is by using pork roast instead of beef. I suggest a pork shoulder or Boston butt roast for the juiciest cuts. 
Drizzling gravy over instant pot Mississippi pot roast.

Serving suggestions:

When I make this roast, I like to serve it with my perfectly creamy mashed potatoes. They are fluffy, buttery, and so smooth. The kids like it when I serve the roast with some creamy mac and cheese on the side. Sometimes, I shred the beef and put it on a bun to serve like au jus dip sandwiches. These are perfect for lunch or dinner. 

When I’m hosting a group, I serve shredded beef with a variety of taco and burrito toppings, along with taco shells and tortillas. I like to have lettuce, shredded cheeses, pickled cabbage, pickled veggies, homemade salsa, sour cream, olives, chopped onions, fresh guacamole, tomatoes, peppers, and beans. 

How to store leftovers:

  • Refrigerate: Pack leftovers in a sealed container in the fridge for up to four days.   
  • Freezing: To freeze, I place leftovers in freezer bags, and they will stay fresh for up to three months.  
  • Defrost: Thaw overnight in the refrigerator for the best flavor.
  • Reheating: I reheat my leftovers in the oven for 10 to 15 minutes at 350 degrees F or in the microwave for one to two minutes. 
Shredded instant pot Mississippi pot roast.

Frequently asked questions

Why is my pot roast rubbery?

It may be that it was not cooked long enough. Check the internal temperature. If it is less than 130 degrees, let it cook for a little bit longer. I would seal it up and cook it for another 10 minutes, and then let it naturally release for five minutes. It could also be due to insufficient liquid. Ensure there is sufficient juice for the proper breakdown of the connective tissue. 

Why is my Instant Pot pot roast dry?

Overcooking it can cause a dry pot roast. If your roast is less than five pounds, it will need a shorter cooking time. This recipe is for a five-pound roast. For a three-pound roast, cook it for 50 minutes, and a four-pound pot roast should be cooked for 60 minutes. Overcooking it will cause it to dry out as it loses its moisture. 

Why am I getting a burn notice?

This should not have happened if the burnt bits had been scraped from the bottom of the pan. But it could also be from not having enough liquid in the pot. This recipe has plenty of liquid, though, so that should not be an issue. Check for obstructions between the inner pot and the heating element. Also, make sure the sealing ring is sealed correctly, the float valve is not stuck, and the steam release switch is in the correct position.  

Can I use frozen meat?

Frozen meat can be used, but it cannot be cut into pieces, so make sure it will fit into the pot. Also, it will have to be cooked for a little bit longer than thawed meat. Just add another 10 minutes to the cooking time. So, it should take about 80 minutes for a five-pound roast. 

Instant pot Mississippi pot roast.

More pot roast recipes to try:

Loved this recipe? I’d love to hear from you! 💛 Leave a 5-star rating ⭐️ in the recipe card below and share your thoughts in the comments – I read and appreciate every single one!

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Overhead shot of tender, instant pot Mississippi pot roast over mashed potatoes.

Instant Pot Mississippi Pot Roast

Instant Pot Mississippi Pot Roast is flavorful and incredibly tender, featuring a rich, buttery gravy, and it cooks in about one hour.
4.89 from 26 votes
Print Pin Rate
Course: Main Course
Cuisine: American
Diet: Gluten Free
Keyword: Mississippi Pot Roast
Prep Time: 30 minutes
Cook Time: 1 hour 10 minutes
Total Time: 1 hour 40 minutes
Servings: 8 people
Calories: 585kcal

Ingredients

  • 5 lbs chuck roast cut into 2 chunks that would fit in the pot
  • 3 tablespoons vegetable or canola oil
  • 1 small onion diced
  • 1 tablespoon minced garlic
  • 1/2 cup water
  • 1/2 cup pepperoncini juice from the jar
  • 3/4 cup beef broth low sodium
  • 1 tablespoon Worcestershire sauce
  • 1/2 teaspoon salt
  • 1/2 teaspoon ground black pepper
  • 1/4 teaspoon red pepper flakes
  • 1 packet of dry Ranch Dressing Mix
  • 1 packet of Au Jus Mix
  • 12 Pepperoncinis whole
  • 1 stick unsalted butter sliced
  • 8 cloves garlic whole
  • 5 bay leaves

Cornstarch Slurry:

  • 2-3 tablespoons cornstarch
  • 3 tablespoons water

Instructions

  • Set Instant Pot to Saute – Normal mode. When it reads "Hot", add the oil and wait for the oil to heat up.
  • Brown the meat in batches. If needed, cut the chuck roast in two so it fits in the pot. Cook each piece on EACH side for a full 5 minutes without turning.
  • If needed, add a bit more oil to the pot when searing the rest of the pieces.
  • Remove the seared pieces on a plate and cover with foil to keep them warm.
  • Once all the beef has been browned and set aside, it's time to deglaze the pot.
  • Add 1/2 cup of water to the pot. Use a wooden spoon to scrape the bits stuck to the bottom and sides of the pot until it's clear.
  • Add onion and minced garlic and cook for 1 minute, stirring occasionally.
  • Add the beef broth, Pepperoncini juice, and Worcestershire sauce.
  • Add the salt, pepper, red pepper flakes, Ranch dressing dry mix, and Au Jus mix. Stir to combine.
  • Turn off the sauté mode.
  • Add the beef in layers, and add sliced butter and garlic cloves between each layer. Add the pepperoncini and the bay leaves to the pot.
  • Close the lid and seal the valve. Cook for 70 minutes on High Pressure. Once the Instant Pot beeps, do a 15 Minute Natural Pressure Release. Release manually the remaining pressure.
  • Open the lid and turn the Instant Pot to Sauté mode.
  • If you want a thicker gravy, mix cornstarch and water in a small bowl until fully combined.
  • Add the mixture to the pot and gently stir. Let it simmer for 2-3 minutes. If you want to thicken it even more, add another round of cornstarch slurry. The sauce will thicken more as it cools off as well.
  • Discard the bay leaves and serve the roast with mashed or baked potatoes. Garnish with extra pepperoncinis and chopped parsley.

Notes

Expert tips

Why browning the chuck roast is important

Browning will lock in all the fantastic flavors and will give the beef that delicious, caramelized top on the outside, which reveals a juicy and tender inside. Also, I highly recommend cutting the chuck roast in half to fit in the Instant Pot. Be sure to brown it well for a few minutes on each side without moving the beef. While you can dump and cook all the ingredients, taking the extra few minutes to brown the meat will make a huge difference in taste and texture.

Using a natural pressure release

One of the most important tips that many people get wrong is to use a natural pressure release after the cooking process. Even if everything is done perfectly and it is cooked exactly as the recipe states, skipping this one step can mess everything up. Allowing the roast to cool slowly in the residual heat makes the meat so much more tender and full of flavor. A quick release instead of a natural release can push the moisture out of the meat and cause it to be dry.

More tips to consider:

  • Find a chuck roast with plenty of marbling for the best results.
  • Season the meat with salt and pepper before searing it.
  • Use unsalted butter. The seasonings have plenty of salt. 
  • Be sure to deglaze the pot to avoid the burn notice. 
  • Chop the butter into small pieces so it melts evenly within the chunks of meat.

Nutrition

Serving: 0g | Calories: 585kcal | Carbohydrates: 6g | Protein: 55g | Fat: 38g | Saturated Fat: 18g | Cholesterol: 195mg | Sodium: 495mg | Potassium: 1060mg | Fiber: 1g | Sugar: 1g | Vitamin A: 135IU | Vitamin C: 21.4mg | Calcium: 64mg | Iron: 6.3mg
4.89 from 26 votes

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75 Comments

  1. OK now this sounds delicious – I have to admit I’ve not tried cooking with an instant pot before but it sounds like you can do so much with one, I need to try it out myself!

  2. This is such a fantastic dinner! Anything I can make in the Instant Pot is a winner in my book!

  3. Wow, I really need to get an Instant Pot and finally make this Mississippi pot roast, looks so good.

    1. You can cook it in your oven or a crock pot. It will take longer but you will get the same great roast.

  4. I don’t make pot roasts nearly enough so thank you for the inspiration! Yours looks so juicy and tender!

  5. This looks like a delicious recipe to try to make. I love all of these Instant Pot recipes everyone is sharing, they are making my tummy growl!

  6. This recipe looks so delicious. The meat looks so supple and flavorful, and not hard to prepare.

  7. My sister makes a roast similar to this in her Instant Pot. I’d like to try your version as well.5 stars

  8. I swear by a good old pot roast meal. This is a super awesome recipe. Thanks so much for sharing all your recipes!

  9. What a unique pot roast recipe. This sounds wonderful and definitely something I’ll try. I don’t cook in our Instant Pot nearly as much as I should!5 stars

  10. I have to confess, I have never mad a pot roast!!! This recipe looks absolutely delicious!

    1. This recipe is not intended to be made with frozen pot roast as I highly recommend browning it first.

  11. That looks delicious! I really need to get me an Instant Pot ASAP so I can cook all these Instant Pot recipes.

  12. I love pot roast but my husband doesnt like it. Its a shame. 🙁 I love mine in a broth, onions, baby carrots, and taters. Yum. I will have to make it soon. Maybe I can twist my husband to try it.5 stars

  13. This recipe looks so good and tasty and this is kind of a perfect dish for lunch or even for a dinner. I will definitely make this recipe for my family.5 stars

  14. I found the same recipe but using a pork roast. It was cooked in a crockpot and used dry onion soup mix with the ranch mix. How long do you think it will need to cook in the instant pot? It showed 6 hours in the crockpot.4 stars

    1. For a cut of pork shoulder or butt recipe that is 2 lbs I would do 10 mins HP & 10 NPR if you pre-slice the pork, or if you add the whole piece, about 40min on HP and 10 NPR, depending on the thickness of the cut you can increase the cooking time to 60 mins on HP and 10NPR.

  15. I’m thawing a 3 pound chuck roast and plan to use your recipe. Will the cook time be any different since my roast is smaller? Thanks, in advance. 

    1. I made the roast according to your recipe with just a few minor changes. It was so delicious! My son asked for the recipe. He and his wife loved it as well. Thanks for your instant pot recipes!5 stars

  16. This looks great. For Instant Pots that let you choose the sauté temperature like the Ultra, do you recommend high or medium to brown the roast? Thanks!

  17. Excellent! I followed the recipe exactly and it was perfection. Probably the best roast I’ve ever had or made! Thank you!5 stars

  18. This looks really good. When I’ve made this before it was just way too salty. I’m going to give this a try and see if it works better for us. I have terrible luck with roast in the Instant Pot, so I’ll do it in the crockpot. Looking forward to trying it tomorrow.

    1. they will be mushy if you add them, I prefer to cook separately. Check my Instant Pot Pot Roast to see how.

  19. This recipe was delicious. I’ve cooked this other times from other recipes with less ingredients. This dish was a real hit on 12/24/18 for our Christmas Eve dinner. The only real substitutions that were made were 1) using 1/2 cup red wine instead in lieu of water to deglaze the pot, 2) omitted the 8 whole garlic cloves since we just did not have any. However, did use the bottled minced garlic from the beginning of the recipe, 3) I used 1/2 cup juice from a bottle of pickled yellow banana peppers in lieu of pepperoncini juice. There were some at the table who cannot tolerate any heat. However, I did add use 10 pepperoncinis for those who wanted a little heat in a bite, and I added about 1/2 cup of the yellow banana peppers. It was a 6.25 pound chuck roast (2 packages) which were stacked on top of each other after browning. The entire roast came out moist, fall apart delicious, and with enough gravy for the dinner AND sufficient enough left over to make some soup for another time. We have the largest Instant Pot (7 or 8 quart), and it was certainly large enough. I must say that one of our guests who generally eats smaller portions and only once, came back for 2nd helpings. He loved it,….All of us loved it.

  20. Received my IP for Christmas. This is my first attempt with this recipe…will see how well it does! Thank you for the inspiration.

  21. Hi, I made this recipe with a few alterations, I put in half the peppers which helped the spice level so it was spicy but still comfortable and I could enjoy it and I used half the au jus packet and half the ranch packet as suggested if you are salt sensitive. It’s still very savory no doubt.  Before storing I actually separated majority of the gravy but not all so that the meat and vegetable would yay juicy and I strained it with a very fine strainer to get all of the pepper seeds out so it would get spicier while stored.  This is a flavorful recipe, and I loved it.  Also I used a 3lb roast and pressure cooked it for 1hr and it came out perfect after searing and following the rest of the normal recipe and also after the meat was done cooking, I used the quick release and added potatoes (red, sliced into 8ths, and carrots sliced into about 1inch by 2-3inches and pressure cooked again for 10 mins on high, then used the natural release for 10 mins and the quick release after that. Voila perfect vegetables and a roast together in one pot.  Overall though with prep and cook time it still took about a couple hours start to finish.  I did not cut my roast in half I left it whole and I seared it for 5 mins on each side.4 stars

    1. Hi and thank you for stopping by. Yes, this dish is super delicious and flavorful, it takes us the same time we post on the recipe card but if you go by larger meat cut it might take a little longer. Glad you have enjoyed it!

  22. I cannot get the dry ranch seasoning packets here, can I use store bought ranch dressing in it’s place? If so, how much would you recommend?

  23. I was wondering, how many pounds of pressure did you set your cooker on? Also, I am trying this with venison/deer roast. This is my sisters Go To pot roast recipe, but my first time trying it in my cooker. Pretty Excited!

  24. I HAVE MADE THIS SEVERAL TIMES, I HAVE SUBSTITUTED PORK LOIN AND CHICKEN BREAST IN PLACE OF POT ROAST AND THINK IT IS BEST WITH THE PORK LOIN. I ADJUST THE SPICE / HEAT LEVEL WITH THE AMOUNT OF PEPPERONCHINI JUICES. I WILL SOMETIMES ADD ASPARAGUS SPEARS ON TOP AND STEAM THEM IN THE INSTANT POT FOR 5 MINUTES AND THEY COME OUT VERY TASTY AS WELL.5 stars

  25. I made this recipe and it came out delicious. I normally make it in the crock pot. This recipe for the instant pot is definitely my new favorite way to cook mississippi pot roast! Thank you for posting it! Family loves it!5 stars

  26. I like your recipe cuz whats different from others is you add onions, garlic and the pepperoncini juice! I tried it and it was delish! Thank you!!5 stars

  27. This was a big hit! My family loved it even though it was an hour late since I suck at cooking and timing things. I don’t cook much, can you tell? I have a rather dumb question though. When browning the roast, there was a lot of grease splatter. I was wondering if I could just lay the lid on the top to prevent the popping of grease. I had a lot of cleanup in my kitchen. I was afraid to do it because it might make the pot too hot. Is there a cover you like to use to prevent the mess? Thanks for this recipe, I think it will become a regular dinner for us.5 stars

  28. How many tablespoons of Ranch Mix is in a packet? I plan to substitute my own dry mix as I am sensitive to MSG. Can’t wait to try this!

  29. I’m not usually the type to come back to a recipe just to comment, but this is THE BEST pot roast I’ve ever made! Also, this was my first Instant Pot recipe, so thank you for making the instructions super clear and helpful! Thank you!5 stars

  30. I love this! I have a slow cooker Mississippi pot roast recipe I make all the time, and this was just as tender and delicious and so much faster!5 stars

  31. This Instant Pot Mississippi Pot Roast turned out amazing! It was easy to prepare and the family loved it…YUMMO!!!5 stars